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The Nation's Investment in Cancer Research Distribution of Fiscal Year 2006 Budget Request ($6,170,000,000)
Distribution of Fiscal Year 2006 Budget Requested Increases ($1,299,975,000)
National Cancer Institute
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| 2006 Budget Request |
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|---|---|---|---|---|---|
| (dollars in thousands) | 2004 Operating Budget | 2005 Congressional Justification | 2006 Increases | 2006 Budget Request | |
| Research Project Grants (RPGs) | |||||
| Ongoing | $1,663,656 | $1,701,664 | $93,818 | $1,795,482 | |
| New and Renewal | 492,369 | 501,682 | 554,163 | 1,055,845 | |
| Subtotal RPGs | 2,156,025 | 2,203,346 | 647,981 | 2,851,327 | |
| Small Business Innovation Research (SBIR) |
99,979 | 103,773 | 26,632 | 130,405 | |
| Total RPGs | 2,256,004 | 2,307,119 | 674,613 | 2,981,732 | |
| Intramural Research | 687,193 | 725,344 | 51,462 | 776,806 | |
| Cancer Centers | |||||
| Comprehensive/Clinical/Basic (P30) | 250,022 | 244,710 | 69,565 | 314,275 | |
| Planning Grants | 0 | 10,815 | 379 | 11,194 | |
| Specialized Center (U54) | 26,088 | 46,272 | 40,120 | 86,391 | |
| Specialized Programs of Research Excellence (SPOREs) |
185,387 | 178,902 | 54,262 | 233,163 | |
| Subtotal Cancer Centers | 461,497 | 480,699 | 164,324 | 645,023 | |
| Clinical Trials Infrastructure | |||||
| Cooperative Clinical Research | 153,882 | 167,330 | 36,957 | 204,287 | |
| Community Clinical Oncology Program (CCOPs) | 95,424 | 98,118 | 32,934 | 131,053 | |
| Subtotal Clinical Trials Infrastructure | 249,306 | 265,448 | 69,891 | 335,339 | |
| Training and Education Grants | |||||
| National Research Service Awards | 66,480 | 70,860 | 8,480 | 79,340 | |
| Research Career Program | 75,346 | 76,812 | 12,888 | 89,700 | |
| Cancer Education Program | 31,769 | 32,006 | 5,120 | 37,126 | |
| Minority Biomedical Research Support | 4,012 | 7,890 | 476 | 8,366 | |
| Subtotal Training and Education Grants | 177,607 | 187,568 | 26,965 | 214,533 | |
| Cancer Control Operations | 143,930 | 157,596 | 9,391 | 166,987 | |
| Research Support Contracts | 538,607 | 504,335 | 245,152 | 749,487 | |
| Research Management and Support | 165,581 | 177,224 | 23,993 | 201,217 | |
| Other Research Grants | 52,473 | 56,692 | 2,184 | 58,876 | |
| Construction | 25,000 | 25,000 | |||
| Repairs and Improvements at NCI-Frederick | 8,000 | 7,000 | 15,000 | ||
| Total Budget Request | 4,732,198 | 4,870,025 | 1,299,975 | 6,170,000 | |
| Cancer Control included above | 521,487 | 544,890 | 135,776 | 680,666 | |
| (dollars in thousands) | Core | Strategic Investments |
Total | |||
| Research Project Grants (RPGs) | ||||||
| Ongoing | $90,318 | $3,500 | $93,818 | |||
| New and Renewal | 263,013 | 291,150 | 554,163 | |||
| Subtotal RPGs | 353,331 | 294,650 | 647,981 | |||
| Small Business Innovation Research (SBIR) | 26,632 | 26,632 | ||||
| Total RPGs | 379,963 | 294,650 | 674,613 | |||
| Intramural Research | 35,387 | 16,075 | 51,462 | |||
| Cancer Centers | ||||||
| Basic/Clinical/Comprehensive (P30) | 63,565 | 6,000 | 69,565 | |||
| Planning Grants | 379 | 379 | ||||
| Specialized Center (U54) | 1,620 | 38,500 | 40,120 | |||
| Specialized Programs of Research Excellence (SPOREs) | 38,262 | 16,000 | 54,262 | |||
| Subtotal Cancer Centers | 103,824 | 60,500 | 164,324 | |||
| Clinical Trials Infrastructure | ||||||
| Cooperative Clinical Research | 5,857 | 31,100 | 36,957 | |||
| Community Clinical Oncology Program (CCOPs) | 3,434 | 29,500 | 32,934 | |||
| Subtotal Clinical Trials Infrastructure | 9,291 | 60,600 | 69,891 | |||
| Training and Education Grants | ||||||
| National Research Service Awards | 2,480 | 6,000 | 8,480 | |||
| Research Career Program | 7,688 | 5,200 | 12,888 | |||
| Cancer Education Program | 1,120 | 4,000 | 5,120 | |||
| Minority Biomedical Research Support | 476 | 476 | ||||
| Subtotal Training and Education Grants | 11,765 | 15,200 | 26,965 | |||
| Cancer Control Operations | 5,516 | 3,875 | 9,391 | |||
| Research Support Contracts | 17,652 | 227,500 | 245,152 | |||
| Research Management and Support | 12,203 | 11,790 | 23,993 | |||
| Other Research Grants | 2,184 | 2,184 | ||||
| Construction | 25,000 | 25,000 | ||||
| Repairs and Improvements at NCI-Frederick | 7,000 | 7,000 | ||||
| Total Increase Request | 609,785 | 690,190 | 1,299,975 | |||
Funding for extramural research, primarily through Research Project Grants (RPGs), comprises the largest part of the NCI core budget. We fund about 4,500 RPGs each year to nearly 600 institutions across the United States at an average cost of approximately $400,000 per grant.
NCI intramural research focuses on projects conducted by some 400 researchers located on the NIH campus. Some of these investigators conduct long-term epidemiologic and genetics studies requiring the continuity of an intramural program. Others work synergistically with other NIH Institutes and with the NIH Clinical Center to quickly transfer laboratory research to the clinic.
Some 60 NCI-supported Cancer Centers serve as hubs for cutting-edge research, high quality cancer care, and outreach and education for healthcare providers and patients. Centers of Excellence like the SPOREs use flexible funding to pursue questions related to specific forms of cancer and to move disease-specific research quickly from the laboratory to the patient.
NCI supports clinical trials at the NIH clinical center and at close to 3,000 other sites across the U.S. Over 1,500 trials are conducted annually, involving more than 12,000 investigators assisting thousands of patients. These trials make possible the testing of targeted agents that hold promise for more effective, less invasive, cancer prevention and treatment and technologies that can be used for better detection and diagnosis.
NCI funds training and education programs involving approximately 170 institutions and 2,000 individuals each year to prepare the next generation of scientists and clinicians to use new technologies and to work effectively in interdisciplinary, collaborative research environments. Increased funding will be used to support the development of interdisciplinary team science and to increase the number of scientists working with underserved populations.
NCI's cancer control operational funds along with numerous grants and contracts included throughout the budget are used to support research, communication, and other activities focused on ways to reduce cancer risk, incidence, morbidity, and mortality and improve the quality of life for all cancer patients. Increases will be used to support research on tobacco and tobacco-related cancers, reducing cancer-related health disparities, improving the quality of cancer care, cancer survivorship, cancer communications, and a host of information dissemination activities.
Research support contracts are used for diverse programs across the Institute. These include drug development, cancer control research, information dissemination, and support to epidemiological research.
Research management and support funds are used for the critical technical and administrative services required for NCI to carry out its work. They cover the cost of central administrative functions, overall program direction, grant and contract review and administration, personnel, program coordination, and financial management.
Other grants support partnerships; shared resources; and scientific evaluation, workshops, and conferences.
